Table 1 Examples of knowledge types represented in DDO ontology
Knowledge type | Definition | Examples |
|---|---|---|
Laboratory test | A set of tests to measure the level of blood glucose, and others | Blood glucose tests: HbA1C, 2Â h OGTT, FPG, RPG |
Hematological profile: prothrombin INR, red cell count, Hbg, hematocrit (PCV), MCV, MCH, MCHC, platelet count, white cell count, basophils, lymphocytes, monocytes, eosinophils | ||
Kidney function laboratory tests: serum potassium, serum urea, serum uric acid, serum creatinine, serum sodium | ||
Lipid profile: LDL cholesterol, total cholesterol, triglycerides, HDL cholesterol | ||
Tumor markers: FERRITIN, AFP serum, CA-125 | ||
urine analysis: chemical examination (protein, blood, bilirubin, glucose, ketones, urobilinogen) Microscopic examination (pus, red blood cells (RBcs), crystals) | ||
Liver function tests: serum albumin, total bilirubin, direct bilirubin, SGOT (AST), SGPT (ALT), alk phosphatase, γ GT, total protein | ||
Females history: amenorrhea, birth, dysmenorrhea | ||
Disease | Diseases that are often present with diabetes (diabetes complications) | Acute: cardiomyopathy, bacterial infection, ketoacidosis, obesity, ovarian disease, neoplastic disease, etc |
Chronic: nonvascular such as dental disease, kidney disease, skin disease, sexual disease, and gastropathy; vascular such as macrovascular and microvascular | ||
Symptom | The set of common diabetes symptoms | Weight loss, polyuria (increased urination), polydipsia (increased thirst), and polyphagia (increased hunger), weight gain, blurred vision, etc |
Drug | The drugs that increase blood glucose, and can induce diabetes either by interfering with insulin production and secretion, reducing the effectiveness of insulin in regulating metabolism, or others | Cardiovascular drugs, CNS drugs, an enzyme inhibitor, a hematologic drug, an immunotherapeutic agent, retinoid, antiallergenic drugs, and others |